Research Bulletin No. 1 In a 4-week feeding trial, Dr. Sung Woo Kim of Texas Tech University, evaluated the efficacy of PepSoyGen as a protein source for 19 day-old weanling pigs.

Research Bulletin No. 2 A 5-week growth performance assay was conducted at South Dakota State University by Dr. Hans Stein to evaluate the efficacy of PepSoyGen as a protein source for 20 day-old weanling pig diets.

Research Bulletin No. 3 The results of this study showed that Aspergillus oryzae GB-107 fermentation significantly changed the physical and nutritional characteristics of high protein soybean meal.

Research Bulletin No. 4 A trial was conducted at Kansas State University by Dr. Joel DeRouchey to evaluate the growth performance effects of including PepSoyGen and DPS in the diets of 15 to 25 lb. pigs.

Research Bulletin No. 5 A field study was conducted in South Dakota to evaluate the effects of including PepSoyGen in the diets of turkey poults from day 0-49 and Natufermen, direct-fed microbial from day 50 to 140 in a natural feeding program. In this study the flocks fed PepSoyGen followed by Natufermen had notably higher body weights at days, 28, 56 and 140 than the control flocks. Additionally, flock uniformity was improved by the addition of PepSoyGen to the diet.

Research Bulletin No. 6 A preliminary 14-day growth performance assay was conducted at D.C. Booth Historic National Fish Hatchery in conjunction with Black Hills State University (Spearfish, South Dakota) to evaluate the efficacy of an innovative direct fed microbial, Natufermen. Natufermen contains a unique balance of a fungi (Aspergillus oryzae) and bacterium (Bacillus subtilis), which in previous monogastric research has shown to improve gut health, and increase feed efficiency.

Research Bulletin No. 7 A 51-day growth performance assay was conducted at D.C. Booth Historic National Fish Hatchery in conjunction with Black Hills State University (Spearfish, South Dakota) to evaluate the efficacy of an innovative direct fed microbial, Natufermen. Natufermen contains a unique balance of a fungi (Aspergillus oryzae) and bacterium (Bacillus subtilis), which in previous monogastric research has shown to improve gut health, and increase feed efficiency.

Research Bulletin No. 8 A trial was conducted by C. K. Jones et al at Kansas State University to evaluate the effects of dietary DPS 50RD, PepSoyGen or fishmeal on of 15-pound pigs in a 28-day, phase 2 growth assay. In this study, piglets fed DPS 50RD or DPS 50RD + PepSoyGen had significantly improved average daily gain and feed efficiency compared to all other dietary treatments, day 0-14 (treatment phase). Overall (day 0-35), pigs fed DPS 50RD day 0-14, had significantly better average daily gain and feed efficiency than the control or PepSoyGen plus fishmeal.

Research Bulletin No. 9 A 28-day trial conducted by B.J. Min et al at Dankook University, Cheonan, Korea evaluated the effects of replacing soy protein concentrate (SPC) with fermented soybean (PepSoyGen) in the starter diet of pigs weaned at 21 days of age. A paper on this study was published in the Asian-Australasian Journal of Animal Science, vol. 22, No. 1: 99-106, January 2009.

Research Bulletin 10 A field evaluation was conducted by a major U.S. turkey producer to determine the effects of feeding Natufermen and PepSoyGen to growing turkeys. The poults were fed a diet containing 5.0% PepSoyGen, day 0-10. From day 11-140, turkeys were fed 0.1% Natufermen and no PepSoyGen. Birds receiving PepSoyGen followed by Natufermen had notably improved feed efficiency, death loss, and market weights.

Research Bulletin 11 The objective of this experiment was to determine the innate immune response of pigs acutely challenged with lipopolysaccharides (LPS) as affected by dietary protein sources either from PepSoyGen (PSG) or spray dried plasma protein (SDPP) when compared to a control soybean meal based diet. The ADG and gain:feed did not differ among treatments during the 15d period. Average serum cortisol concentration of PSG was significantly lower (P<0.05) than CON, but did not differ from SDPP.

Research Bulletin 12 A 49 day growth, diarrheal incidence, and immune response trial utilizing Holstein calves was performed at the Dairy Science Division at the National Institute of Animal Science, Cheonan, South Korea. Researchers have noted that replacement of conventional soybean meal with 5% PepSoyGen (fermented soybean meal) in pelleted calf starter diets alleviated diarrhea and increased the production of immune-related effector cells such as IgA and haptoglobin. No differences were observed for growth performance or feed intake.

Research Bulletin 13 Dr. Sung Woo Kim of North Carolina State University conducted two experiments to determine the efficacy of partial replacement of dried skim milk (DSM) with PepSoyGen (PSG) in the diets of weanling pigs. Trial 1 demonstrated that PepSoyGen can be included at up to 6% of the diet at the expense of dried skim milk, while maintaining ADG and ADFI. In trial 2, piglets fed a diet including PepSoyGen at up to 10% at the expense of DSM had improved growth performance relative to piglets fed just DSM, when lactose levels were equal across dietary treatments.

Research Bulletin 14 An experiment was conducted by Dr. Sung Woo Kim of North Carolina State University, to determine the relative bioavailability of PepSoyGen to spray-dried porcine plasma. This trial indicated that overall the relative bioavailability of PepSoyGen to spray-dried plasma protein during the experimental period was 111.2%. Overall ADG of the PepSoyGen fed pigs and the plasma fed pigs was not different. However, the pigs fed the higher level of PepSoyGen had better overall feed efficiency than either of the plasma protein treatments.

Research Bulletin 16 A trial conducted at Cheonan Yonam College, Korea evaluated the growth effects of feeding the direct-fed microbial (DFM), Lactocare or DFM B on weanling and grower pigs. Lactocare is manufactured using fermented fruits by Genebiotech Co., Ltd, Korea.
In the starter phase, data showed that the Lactocare replaced the competitor’s product at 0.1% of the diet with equal performance.

Research Bulletin 17 An experiment conducted by S.W. Han et al at Chungnam National University, Daejeon, Korea evaluated the effects of feeding Aspergillus oryzae (AO) culture to laying hens. The study examined AO effects on fecal microbial populations, fecal pH and moisture content, egg quality and the metabolizability of gross energy, dry matter, crude protein and crude fat.

Research Bulletin 18 Two experiments were conducted in 2010 by O.J. Rojas and H.H. Stein of the University of Illinois, Urbana, to measure the apparent amino acid and phosphorus digestibility of PepSoyGen in weanling pigs.

Research Bulletin 19 Two experiments were conducted in 2004 at Dankook University, Cheonan, Korea by B.J. Min et al, to evaluate the effects of feeding processed soy protein products on the growth performance and apparent amino acid ileal digestibility in weanling pigs. The two products were PepSoyGen, fermented soybean meal product and a competitor’s enzymatically treated soy product (ETS).

Research Bulletin 20 Two trials were conducted by a major Canadian swine integrator, to evaluate the effects of including PepSoyGen in the diets of weanling pigs on post-weaning growth performance. PepSoyGen was included at the expense of herring meal in the diets of pigs weaned a 21 days of age.

Research Bulletin 21 A forty-seven day trail was conducted by a major U.S. feed manufacture to test PepSoyGen (PSG) plus DPS (50 RD) and an experimental porcine digest (EPD) on the growth performance and feed utilization of weanling pigs in a commercial setting.

Research Bulletin 22 The objective of this experiment was to quantify the effects of Natufermen supplementation (0.2%) on the gut integrity of growing broiler chicks challenged with a 10X dose of attenuated coccidial vaccine as a disease challenge or challenged by built-up litter (un-cleaned from previous two flocks).

Research Bulletin 23 A weanling pig trial was conducted at the University of Illinois by O. Rojas, 2011 to determine the effects on growth performance of replacing chicken meal (CM), poultry by-product meal (PBM) or fishmeal (FM) in the diets with PepSoyGen (PSG).

Research Bulletin 24 A seventy day trail was conducted at the McNenny State Fish Hatchery in South Dakota to test PepSoyGen (PSG) replacement of fishmeal on the growth performance and feed utilization of juvenile rainbow trout. Six experimental diets containing 0, 10, 20, 30, 40, or 50% PSG were utilized for this trial replacing equal portions of Herring meal. Typically soy proteins in salmonid diets are low because of the presence of trypsin inhibitors, lectins, saponins, and non-digestible carbohydrates.

Research Bulletin 25 In a 2012, eight-week feeding trial conducted by Dr. Jesse Trushenski et. al. at Southern Illinois University, production performance was assessed for juvenile striped bass. The effects of replacing dietary fishmeal (FM) with PepSoyGen (PSG) or soybean meal (SBM) were evaluated.

Research Bulletin 26: The objective of this experiment was to quantify the effects of Natufermen® supplementation (0.2%) on the gut integrity of growing broiler chicks challenged with a 10X dose of attenuated coccidial vaccine as a disease challenge or challenged by built-up litter (un-cleaned from previous two flocks).